Autoimmune Blood Tests: When Your Body Attacks Itself

Women account for 78% of autoimmune disease cases. If you're experiencing unexplained symptoms, autoimmune testing may provide answers.

What Are Autoimmune Diseases?

In autoimmune conditions, your immune system mistakenly attacks your own tissues. There are over 80 types, including:

• Hashimoto's thyroiditis
• Rheumatoid arthritis
• Lupus
• Celiac disease
• Multiple sclerosis
• Type 1 diabetes

Common Autoimmune Symptoms

• Fatigue
• Joint pain and swelling
• Skin problems
• Digestive issues
• Recurring fever
• Swollen glands

Autoimmune Screening Tests

ANA (Antinuclear Antibody)

A screening test for many autoimmune conditions. Positive ANA doesn't confirm disease but warrants further investigation.

Specific Antibodies

• Thyroid antibodies (TPO, TgAb) - Hashimoto's
• RF and anti-CCP - Rheumatoid arthritis
• Anti-dsDNA, Anti-Smith - Lupus
• Anti-tTG, Anti-EMA - Celiac disease

Inflammatory Markers

• CRP (C-reactive protein)
• ESR (sed rate)
• Ferritin (can be elevated in inflammation)

Important Notes

• Autoimmune diseases often cluster
• Diagnosis can take years
• Early detection improves outcomes
• Lifestyle factors can influence disease activity

References

• Jacobson, D. L., et al. (1997). Epidemiology and estimated population burden of selected autoimmune diseases in the United States. Clinical Immunology and Immunopathology, 84(3), 223-243.
• Fairweather, D., & Rose, N. R. (2004). Women and autoimmune diseases. Clinical Immunology, 10(11), 2-10.