Low Energy? Blood Tests That Can Help Explain Why
Feeling tired all the time isn't normal - it's a symptom. The right blood tests can help identify why your energy is depleted.
Common Causes of Low Energy
- Iron deficiency (with or without anemia)
- Thyroid dysfunction
- B12 deficiency
- Vitamin D deficiency
- Blood sugar problems
- Chronic inflammation
- Poor sleep quality
The Energy Panel
Iron Status - Ferritin (most important) - Serum iron - TIBC - Transferrin saturation - CBC
Thyroid - TSH - Free T3 (the active hormone) - Free T4 - Thyroid antibodies
Vitamins - Vitamin B12 - Vitamin D - Folate
Metabolic - Fasting glucose - HbA1c - Fasting insulin
Inflammation - CRP - Ferritin (also elevated in inflammation)
The Most Missed Tests
Doctors often skip: - Ferritin: Checked only if CBC is abnormal - Free T3: Only TSH is checked - Fasting insulin: Only glucose is checked
These are often the most revealing tests for unexplained fatigue.
When Results Are "Normal"
If all results are normal but you're still tired: - Look at optimal vs. normal ranges - Consider additional testing (cortisol, sex hormones) - Evaluate sleep quality - Assess stress levels
References
- Vaucher, P., et al. (2012). Effect of iron supplementation on fatigue in nonanemic menstruating women with low ferritin: a randomized controlled trial. *Canadian Medical Association Journal*, 184(11), 1247-1254.
- Stabler, S. P. (2013). Clinical practice: vitamin B12 deficiency. *New England Journal of Medicine*, 368(2), 149-160.
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