80% of autoimmune patients are women.
If your body is attacking itself, these markers will show it.
Autoimmune diseases take an average of 4.5 years and 4 doctors to diagnose. This panel screens for the antibodies and inflammatory markers that reveal autoimmune activity — often years before a clinical diagnosis.
Why this matters for women
Autoimmune diseases disproportionately affect women — 80% of patients are female. Conditions like Hashimoto's thyroiditis, lupus, rheumatoid arthritis, and Sjogren's syndrome often start with vague symptoms: fatigue, joint pain, brain fog, skin changes, and digestive issues. These symptoms are routinely dismissed as stress, anxiety, or "getting older." The average autoimmune patient sees 4 doctors over 4.5 years before getting a diagnosis. During that time, antibodies are actively attacking healthy tissue. The earlier you catch autoimmune activity, the earlier you can intervene. This panel tests for ANA (the broad autoimmune screening marker), specific antibodies for lupus, rheumatoid arthritis, and Hashimoto's, plus inflammatory markers that show how active the immune response is.
Symptoms to watch for
What we test
ANA Screen
Antinuclear antibody test — the primary screening tool for autoimmune disease. A positive ANA doesn't diagnose a specific condition, but it signals that your immune system is producing antibodies against your own tissue.
Sm/RNP Antibodies
Specific markers for lupus and mixed connective tissue disease. These antibodies target proteins in your cell nuclei and are highly specific for systemic autoimmune conditions.
dsDNA Antibodies
Double-stranded DNA antibodies are the most specific marker for systemic lupus erythematosus (SLE). Levels often correlate with disease activity and can predict flares.
Rheumatoid Factor
An antibody found in approximately 80% of rheumatoid arthritis patients. Can be elevated years before joint symptoms appear, enabling early intervention.
CCP Antibody
Anti-cyclic citrullinated peptide antibody — highly specific for rheumatoid arthritis and often positive before symptoms develop. More specific than rheumatoid factor alone.
TPO Antibodies
Thyroid peroxidase antibodies — the hallmark of Hashimoto's thyroiditis, the most common autoimmune disease in women. Can be elevated for years while TSH remains "normal."
hs-CRP
High-sensitivity C-reactive protein measures systemic inflammation. Elevated in active autoimmune disease, infections, and cardiovascular inflammation. Useful for tracking disease activity.
Sed Rate (ESR)
Erythrocyte sedimentation rate — a general inflammation marker that complements hs-CRP. Elevated ESR is common in autoimmune flares, infections, and inflammatory conditions.
Who should consider this panel
- Women with unexplained chronic fatigue, joint pain, or brain fog
- Anyone with a family history of autoimmune disease
- Women with symptoms that multiple doctors can't explain
- Those with a positive ANA who need more specific testing
- Women experiencing hair loss, skin rashes, or dry eyes/mouth
Cited sources
The Prevalence of Autoimmune Disorders in Women: A Narrative Review
Angum F, et al. Cureus, 2020.
Anti-CCP Antibody, a Marker for the Early Detection of Rheumatoid Arthritis
van Venrooij WJ, et al. Annals of the New York Academy of Sciences, 2008.
Hashimoto's Thyroiditis: Epidemiology, Pathogenesis, Clinic and Therapy
Ragusa F, et al. Best Practice & Research Clinical Endocrinology & Metabolism, 2019.
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You're not imagining it. Get the autoimmune screening that validates what you're feeling.